Revisión bibliográfica de estudios sobre la aplicación de células madre mesenquimales en lesiones musculo-esqueléticas o en artrosis. equinas: capacidad inmuno-moduladora in vitro e in vivo de las células madre mesenquimales de médula ósea (bm-mscs) en un modelo de artritis inducida. Células troncales mesenquimales: potencial de terapia celular en trasplante de células troncales hematopoyéticas. Residente ; 9 (2). Idioma: Español.
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Células madre mesenquimales para la regeneración de tejidos: ¿Por qué siguen siendo una promesa sin cumplir? Epub /09/ 2. sobre las células troncales mesenquimales de especies do- mésticas y se discuten Palabras clave: células troncales mesenquimales, médula ósea, diferenciación celular J. Feline Med. Surg. Feb 17 in press [Epub ahead of print]. Year/Month, Html, Pdf, Epub, Total. June, , 81, 6, , , 37, 0, April, , 49, 0, March, , 35, 0,
Stem cell plasticity: time for a reappraisal? Plasticity of marrow-derived stem cells. The therapeutic potential of stem cells. Salem HK, Thiemermann C. Mesenchymal stromal cells: current understanding and clinical status. Stem Cells.
Once adipose tissue is obtained and treated enzymatically to remove extracellular proteins, stem cells can be separated from mature adipocytes by centrifugation, taking advantage of the low density of the adipocytes floating in the isolation medium.
The cells at the bottom of the centrifuge tube, called the vascular stromal fraction, contain the so-called ASC adipocyte stem cell or adipocyte stem cells. The beneficial effect of parathyroid hormone PTH on the bone is widely recognized [ 3 , 4 ]. When the hormone is administered intermittently, it can activate the parathormone 1 receptor PTH1R , triggering an increase in the number of osteoblasts, which leads to increased bone formation and bone mass.
Similar to PTH, clinical studies have shown that fragments containing the N-terminal region of PTHrP increase bone mass in postmenopausal women with osteoporosis. Vascular endothelial growth factor VEGF is a cytokine produced by cells that are part of, or directly associated with, blood vessels [ 6 ].
VEGF is also produced by osteoblasts and participates in the development of endochondral, intramembranous bone and bone repair.
The research group that carried out this study [ 2 ] previously demonstrated the role of receptors for PTH and VEGF in the response of osteocytes to mechanical impulses [ 7 , 8 ].
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