Dr Leon Speroff, Professor Emeritus and former Chair of Obstetrics and Gynecology at the Oregon Health & Science University School of Medicine and former. ed, by Leon Speroff, Robert H. Glass, and Nathan C. Kase, pp, with illus, $47 Infertility, by Speroff, Glass, and Kase, follows the format of the Gynecology. Department of Obstetrics and Gynecology, Baylor College of Medicine, Houston, The new Speroff Clinical Gynecologic Endocrinology and Infertility, in its 7th.
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Clinical Gynecologic Endocrinology and Infertility 6th ed: Leon Speroff, Robert H. Glass, Nathan G. Kase, Lippincott Williams & Wilkins. By OkDoKeY. Dr Leon Speroff, Professor Emeritus and former Chair of Obstetrics and. Gynecology at the Oregon Health & Sci- ence University School of Medicine and. of ultrasound to obstetrics and gynecology has made tremendous. Speroff L, Fritz MA. Clinical DC Dutta's Textbook of Gynecology, 6th ronaldweinland.info
Leon has made seminal contributions to reproductive endocrinology, including key concepts in the regulation of the human menstrual cycle, 1 the role of prostaglandins in ovulation, 2 , 3 induction of myometrial contractility, 3 — 5 induction of labor, 5 — 7 and midtrimester termination of pregnancy 7 — 9 in addition to the development of radioimmunoassays for primary prostaglandins and their metabolites. Leon, with Nathan Kase and Robert Glass, and subsequently with Marc Fritz, wrote the book Clinical Gynecologic Endocrinology and Infertility Figure 1 , 22 a true medical best-seller, which has been a vademecum and has taught generations of physicians. Now in its eighth edition, the book has been translated into, among other languages, Chinese, Spanish, Italian, Greek, Farsi, Portuguese, Polish, and Turkish. Since the first edition appeared in , the English version of the book has sold nearly , copies throughout the world. Robert Glass and Nathan Kase. Leon was born and raised in Ohio, where he also attended college and medical school.
Wade and Doe v. Bolton : "ruled that the state's interest in the life of the fetus became compelling only at the point of viability, defined as the point at which the fetus can survive independently of its mother. Even after the point of viability, the state cannot favor the life of the fetus over the life or health of the pregnant woman. Under the right of privacy, physicians must be free to use their "medical judgment for the preservation of the life or health of the mother.
Bolton, in which the Court defined health very broadly: "The medical judgment may be exercised in the light of all factors—physical, emotional, psychological, familial, and the woman's age—relevant to the well-being of the patient. All these factors may relate to health.
This allows the attending physician the room he needs to make his best medical judgment. Unable to obtain a legal abortion in the United States, she traveled to Sweden. From to , an outbreak of German measles left 15, babies with severe birth defects. In , the American Medical Association publicly supported liberalization of abortion laws. This is particularly true for cervical cancer , the most common type of which occurs in 1 of every 2,—13, pregnancies, for which initiation of treatment "cannot co-exist with preservation of fetal life unless neoadjuvant chemotherapy is chosen ".
Very early stage cervical cancers I and IIa may be treated by radical hysterectomy and pelvic lymph node dissection, radiation therapy , or both, while later stages are treated by radiotherapy. Chemotherapy may be used simultaneously.
Treatment of breast cancer during pregnancy also involves fetal considerations, because lumpectomy is discouraged in favor of modified radical mastectomy unless late-term pregnancy allows follow-up radiation therapy to be administered after the birth. Treatment with more than 40 Gy of radiation usually causes spontaneous abortion.
Exposure to much lower doses during the first trimester, especially 8 to 15 weeks of development, can cause intellectual disability or microcephaly , and exposure at this or subsequent stages can cause reduced intrauterine growth and birth weight.
Exposures above 0. An example of a clandestine advertisement published in a January edition of the Boston Daily Times. Since ancient times abortions have been done using herbal medicines , sharp tools, with force , or through other traditional methods. Author manuscript; available in PMC Jun 5. Author information Copyright and License information Disclaimer.
The publisher's final edited version of this article is available at Am J Obstet Gynecol. See other articles in PMC that cite the published article. Figure S2. JPG 1. Legends S1-S2.
Open in a separate window. A medical best-seller Dr. Education in obstetrics and gynecology and steroid hormones Leon decided to become a physician in his senior year of college. Toward understanding the endocrinological control of the menstrual cycle. Academic career and authorship in reproductive endocrinology Leon intended to spend two years at Columbia University, but after his first year, Nate, who had become Chair at Yale in , asked Leon to return, which he did during the summer of A new approach to contraception Executives of the Parke-Davis Pharmaceutical Company approached Leon in and asked for his advice on how to compete with the multiphasic oral contraceptives that were popular at the time.
Leon, an author, outside medicine Leon indulged his passion and great gift as a storyteller and has written several nonmedical books.
Leon at leisure: Supplementary Material Figure S1 Click here to view.
Figure S2 Click here to view. Legends S1-S2 Click here to view. References 1. Regulation of the human menstrual cycle. The effects of an inhibitor of prostaglandin synthesis indomethacin on ovulation, pregnancy, and pseudopregnancy in the rabbit. Prostaglandins in the control of ovulation, corpus luteum function, and parturition.
J Reprod Med. Intravenous prostaglandins E2 and F2 and syntocinon for the induction of term labor. The use of prostaglandins for the induction of labor. Intravenous prostaglandins E2 and F2 for the induction of term labor. Clinical use of prostaglandins as oxytocin substances. Ann N Y Acad Sci.
Midtrimester abortion using intraamniotic prostaglandin F2alpha. The induction of therapeutic abortion using intravenous prostaglandin F2 alpha. Radioimmunoassay of the F prostaglandins.
J Clin Endocrinol Metab. Radioimmunoassay of the A prostaglandins. Development and application of a radioimmunoassay for F prostaglandins.
A radioimmunoassay for 13, dihydroketo prostaglandin F2alpha with chromatography and internal recovery standard. Prevention of endotoxin induced death in rabbits with indomethacin. Clin Res. Ovulation and pregnancy rates with clomiphene citrate. Obstet Gynecol. Rowan JP. A study of combined continuous ethinyl estradiol and norethindrone acetate for postmenopausal hormone replacement.
Reduced vaginal bleeding in postmenopausal women who receive combined norethindrone acetate and low-dose ethinyl estradiol therapy versus combined conjugated equine estrogens and medroxyprogesterone acetate therapy.
The comparative effect on bone density, endometrium, and lipids of continuous hormones as replacement therapy CHART study. A randomized controlled trial. Speroff L.
WHI trial: What have we learned from the WHI? Clinical gynecologic endocrinology and infertility. Baltimore MD: Dick-Read G. Childbirth without fear: New York NY: Harper; Mathematical studies of the human menstrual cycle. Formulation of a mathematical model. Regulation of human gonadotropins. Episodic fluctuation of LH during the menstrual cycle. Toxemia of pregnancy.
Mechanism and therapeutic management. Am J Cardiol. Speroff L, Ramwell PW. Prostaglandin stimulation of in vitro progesterone synthesis. Jensen JT, Speroff L. Health benefits of oral contraceptives.
Obstet Gynecol Clin North Am. Postmenopausal hormone therapy and the risk of breast cancer: Carlos Montezuma, M. Portland OR: Arnica Publishing; The Deschutes River railroad war. A good man, Gregory Goodwin Pincus: A slow-pitch summer: Slow-pitch therapy: site Digital Services; Harrari YN. London United Kingdom: Vintage;