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Dermatitis herpetiformis was first described by Louis. Adolphus .. Sanjinés L, Martínez M, Magliano J. Dermatitis herpetiforme como carta de. Keywords: Celiac disease, Dapsone, Dermatitis herpetiformis, Diet, gluten-free, Transglutaminases Dermatite herpetiforme e dermatose por IgA Linear; pp. La dermatitis herpetiforme constituye una enfermedad crónica, hereditaria, de base inmune, que afecta preferentemente a la población del norte de Europa.

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La dermatitis herpetiforme constituye una enfermedad crónica, hereditaria, de base inmune, que afecta El Texto completo solo está disponible en PDF. Download PDF La dermatitis herpetiforme es una enfermedad ampollosa autoinmune que aparece como expresión cutánea de la intolerancia al gluten. text new page (beta); English (pdf) · Article in xml format; How to cite this article; SciELO Dermatitis herpetiformis (DH) or Duhring-Brocq disease is a chronic bullous Dermatite herpetiforme é uma doença bolhosa crônica caracterizada por.

Palabras clave: dermatitis herpetiforme intolerancia al gluten Dermatitis herpetiforme is a chronic, hereditary disease having an immune basis. It preferentially affects the Northern Europe population. Its approximate frequency is one case per every ten thousand persons and it predominates in males with a 1. At present, it is considered to be a manifestation form of celiac disease CD , the participation of gluten being clearly demonstrated in its development. Clinically, it is characterized by vesicle-bullous type skin lesions, accompanied by intense itching.

It is likely that some cases initially described were of bullous pemphigoid or linear IgA dermatosis bullosa, given the unavailability of better diagnostic tools at that period. In Civatte demonstrated that, in pemphigus, the formation of blisters was intraepidermal, differently from bullous pemphigoid and DH, which present subepidermal alterations.

In Van der Meer, in turn, revealed the occurrence of granular IgA deposits in those same locations, which constituted a major milestone for the understanding of this disease and permitted for the first time its differentiation from linear IgA dermatosis bullosa. Studies conducted in Scotland and Sweden found an incidence of It affects predominantly Caucasians compared to African-Americans or Asians.

In the latter, besides being rare, the disease is characterized by often not being associated with CD, besides the prevalence of fibrillar IgA deposits on direct immunofluorescence, and a different HLA pattern. On gender incidence, males predominate in a ratio of compared to females, but in younger individuals this ratio is reversed, with affected females being more prevalent. Hervonen evaluated 6 pairs of twins, and noted that 3 pairs had DH, and in 2 pairs one twin had DH and the other had CD, and also in just a pair, one twin had DH and the other none of the diseases.

Despite the probable similar genetic origin, environmental factors may influence the occurrence of either pathology. DH and CD are significant examples of pathologies in which environmental factors participate in the physiopathogeny. Dieterich et al first described them in , suggesting that this was the primary autoantigen recognized by IgA in CD and DH.

TTG is widely distributed in the human body, and is considered a surrogate marker for CD diagnosis.

Herpetiforme pdf dermatitis

Kosan MK. Dermatitis herpetiformis. Dermatol Online J. Coeliac disease presenting as dermatitis herpetiformis in infancy. J Paediatr Child Health.


Dermatitis herpetiformes: should direct immunofluorescence be the only diagnostic criterion? Pediatr Dermatol.

Dermatitis herpetiformis: celiac disease of the skin. Report of two cases

Clinical, pathologic and immunopathologic features of dermatitis herpetiformes: review of the Mayo Clicic experience. Int J Dermatol.

Clinical, histological and immunpathological findings in 32 patients with dermatitis herpetiformis Duhring. J Dtsch Dermatol Ges. Guidelines for the diagnosis and treatment of dermatitis herpetiformis. J Eur Acad Dermatol Venereol. J Clin Invest. Br J Dermatol. Epidermal transglutaminase TGase 3 is the autoantigen of dermatitis herpetiformis. J Exp Med. Distinct TCR delta repertoires are present in the cutaneous lesions and inflamed duodenum of patients with dermatitis herpetiformis.

Exp Dermatol. In patients with dermatitis herpetiformis distribuition of transglutaminase in cutaneous tissue does not differ from controls.

Dig Liver Dis. Lacerda, Liziane D. Gondim AJC. Immunoglobulin, complement and epidermal transglutaminase deposition in the cutaneous vessels in dermatitis herpetiformis. Permeability, zonulin production, and enteropathy in dermatitis herpetiformis. Clin Gastroenterol Hepatol. Sitaru C, Zilikens D.

L'Oberta en Obert: Intolerancia al gluten y dermatitis herpetiforme : ¿Causa-efecto?

Mechanisms of blister induction by autoantibodies. Hypokalemic myopathy in a patient with glutensensitive enteropathy and dermatitis herpetiformis Duhring: a case report. World J Gastroenterol. Select parameters of fibrinolysisi system in patients with dermatitis herpetiformis.

Pdf dermatitis herpetiforme

Med Sci Monit. Blistering diseases in the elderly: diagnosis and treatment. Dermatol Clin. Medicina Interna. Rio de Janeiro: Mc Graw Hill; The occurrence of type 1 diabetes in patients with dermatitis herpetiformis and their first-degree relatives.

Inflamatory epidermolysis bullosa mimicking toxic epidermal necrolusis and dermatitis herpetiformis.

Clin Exp Dermatol. Lymphoma in patients with dermatitis herpetiformis and their first-degree relatives. Cancer incidence in a population-based cohort of individuals hospitalized with celiac disease or dermatitis herpetiformes. No increase in risk of fracture, malignancy or mortality in dermatitis herpetiformis: a cohort study.

Aliment Pharmacol Ther. Fibrillar IgA deposition in dermatites herpetiformis - an underreported pattern with potential clinical significance.

J Cutan Pathol. J Invest Dermatol. Gluten intolerance: Gender and age-related differences in symptoms.

Scand J Gastroenterol. Oats Can Diversify a gluten-free diet in celiac disease and dermatitis herpetiformis. J Am Diet Assoc. Korman NJ. New immunomodulating drugs in autoimmune blistering diseases. Glied M, Rico MJ. Treatment of autoimmune blistering diseases.

Pdf dermatitis herpetiforme

Severe Dapsone Hypersensitivity Syndrome. J Investig Allergol Clin Immunol. Dexamethasone-cyclophosphamide pulse therapy for autoimmune-vesiculobullous disorders at Victoria hospital, Bangalore.

Herpetiforme pdf dermatitis